Brufen 400mg Effervescent Granules 20 sachets

Brufen 400mg Effervescent Granules 20 sachets

Non-prescription drug indicated in the symptomatic treatment of mild to moderate acute pain.

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Brufen 400mg is indicated for the symptomatic treatment of mild to moderate acute pain such as headache and toothache. Primary dysmenorrhea. Fever. In adults and adolescents over 12 years of age (≥ 40 kg)

Active substance : 400mg ibuprofen.

Dosage and method of administration:

Undesirable effects can be minimized by using the lowest effective dose for the shortest period of time necessary to control symptoms. The dose of ibuprofen depends on the patient's age and body weight. The maximum single daily dose for adults and adolescents should not exceed 400 mg of ibuprofen. Adults and adolescents over 12 years of age (≥ 40 kg). 400 mg given as a single dose or up to 3 times a day, 4 to 6 hours apart. More than 400 mg at a time will not give you a better analgesic effect. The maximum daily dose should not exceed 1200 mg. In order to have a faster onset of action, the dose can be taken on an empty stomach. It is recommended that patients with sensitive stomachs take ibuprofen with food. The effervescent granules must be mixed with water to make an orange-flavored effervescent drink. Empty the contents of one sachet into a glass of water, shake and drink immediately. The contents of the sachet cannot be divided into equal doses, and the entire contents of the sachet must be used. Brufen may cause a transient burning sensation in the mouth or throat; ensure that the granules are dissolved in plenty of water.


Hypersensitivity to the active substance or to any of the excipients. Previous hypersensitivity reactions (eg asthma, rhinitis, urticaria or angioedema) in response to aspirin or other NSAIDs; history of gastrointestinal bleeding or perforation related to previous NSAID therapy; active peptic ulcer/bleeding or history of recurrent peptic ulcer/bleeding (two or more distinct proven episodes of ulceration or bleeding); severe liver or kidney failure; severe heart failure (NYHA class IV) or coronary heart disease; last trimester of pregnancy; significant dehydration (caused by vomiting, diarrhea or insufficient fluid intake); cerebrovascular or other active bleeding; dysematopoiesis of unknown origin; children under 12 years of age.

If in doubt or if symptoms persist, consult your doctor or pharmacist.

In accordance with current legislation, non-prescription medicines in Portugal can only be delivered to the municipalities of Maia, Gondomar, Matosinhos, Porto, Santo Tirso, Trofa, Valongo and Vila do Conde. This limitation does not apply to shipments to other Member States of the European Union.