UpCard 3mg 100 tablets
Treatment of clinical signs related to congestive heart failure in dogs.
For the treatment of clinical signs, including edema and stroke related to congestive heart failure.
Composition: Torasemide 3mg
Torasemide is a loop diuretic of the pyridyl sulfonylurea class. Torasemide is secreted in the lumen of the tubules through the transport system of organic acids sensitive to probenecid. The main site of action is the medullary part of the ascending branch of the loop of Henle. Loop diuretics mainly inhibit Na + / 2Cl / K + transporter from the luminal side of the cell. Inhibition of the reabsorption of sodium and chloride ions not only results in saluresis, but also a decrease in interstitial osmolarity within the renal medulla. This, in turn, decreases the reabsorption of free water, resulting in an increase in the production of water / urine excretion. In normal dogs and after administration once daily for 5 days, the average percentage increase in urine excreted over 24 hours varied between 33% and 50% at 0.15 mg / kg, between 181% and 328% 0.4 mg / kg and between 264% and 418% at 0.75 mg / kg.
Posology and route of administration:
The veterinary medicinal product can be administered with or without food. The recommended dose of torasemide is 0.1 to 0.6 mg / kg body weight, once daily. Most dogs are stabilized with a dose of torasemide below 0.3 mg / kg body weight, once a day.
Because it is a veterinary medicinal product subject to medical prescription, we request to send it to the email: [email protected]